WDR5 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | WDR5 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine, rat, Drosophila) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This WDR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5. Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. |
| Immunogen | n/a |
| Other Names | [WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; WDR5; BIG3] |
| Gene, Accession # | [WDR5], Gene ID: 11091, NCBI: NP_060058.1, UniProt: P61964 |
| Catalog # | MBS9213198 |
| Price | $165, $370 |
| Order / More Info | WDR5 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Young J.M.,et al.Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Wysocka J.,et al.Genes Dev. 17:896-911(2003). Hughes C.M.,et al.Mol. Cell 13:587-597(2004). Yokoyama A.,et al.Mol. Cell. Biol. 24:5639-5649(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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