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Antigenic Specificity | Human CD14 |
Clone | [hCD4] |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells. |
Immunogen | Immunogen: Purified human B Cells Ig SubclassMouse IgG1. Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/106 cells. |
Other Names | [CD14; CD14, Mouse Human; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein], [NDUFA2; NDUFA2; B8; CD14; CIB8; CI-B8] |
Gene, Accession # | [CD14], Gene ID: 4695, NCBI: NP_001171941.1 |
Catalog # | MBS140130 |
Price | $305, $455 |
Order / More Info | Human CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |