RICTOR (Center) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RICTOR (Center) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RICTOR (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RICTOR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1068-1102 amino acids from the Central region of human RICTOR. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308 |
| Immunogen | n/a |
| Other Names | [Rapamycin-insensitive companion of mTOR; AVO3 homolog; hAVO3; RICTOR {ECO:0000312|EMBL:EAW559801}] |
| Gene, Accession # | [RICTOR], Gene ID: 253260, NCBI: NP_001272368.1, UniProt: Q6R327 |
| Catalog # | MBS9207243 |
| Price | $165, $370 |
| Order / More Info | RICTOR (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sarbassov D.D.,et al.Curr. Biol. 14:1296-1302(2004). Bechtel S.,et al.BMC Genomics 8:399-399(2007). Schmutz J.,et al.Nature 431:268-274(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Ohara O.,et al.DNA Res. 9:47-57(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies