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Antigenic Specificity | Human CDH1 / E Cadherin |
Clone | [3F4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 0.4 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA), Proximity Ligation Assay |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E Cadherin (CDH1) is a classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. |
Immunogen | Immunogen Description: CDH1 (NP_004351, 381 a.a. ~ 481 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Other Names | [CDH1 / E Cadherin (clone 3F4) IHC-plus; CDH1; CD324; CDHE; Cell-CAM 120/80; E Cadherin; E-Cadherin; ECAD; Epithelial cadherin; Arc-1; UVO; Cadherin-1; CAM 120/80; CD324 antigen; LCAM; Uvomorulin; Human CDH1; E Cadherin], [CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDHE; UVO; E-cadherin] |
Gene, Accession # | [CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830 |
Catalog # | MBS246625 |
Price | $605 |
Order / More Info | Human CDH1 / E Cadherin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |