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Antigenic Specificity | FGR - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FGR |
Other Names | [tyrosine-protein kinase Fgr; Tyrosine-protein kinase Fgr; tyrosine-protein kinase Fgr; FGR proto-oncogene, Src family tyrosine kinase; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; Proto-oncogene c-Fgr; p55-Fgr; p58-Fgr; p58c-Fgr] |
Gene, Accession # | [FGR], Gene ID: 2268, NCBI: NP_001036194.1, UniProt: P09769 |
Catalog # | MBS3220265 |
Price | $335 |
Order / More Info | FGR - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |