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Antigenic Specificity | CD320 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD320 antibody detects endogenous levels of total CD320. Function: Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631). CD320 augments the pro |
Immunogen | Immunogen: A synthesized peptide derived from human CD320 Subcellular Location: Membrane. Tissue Specificity: Detected in the germinal center (GC) of lymphoid follicles (at protein level) (PubMed:11418631). Expressed abundantly on follicular dendritic cells (FDCs) (PubMed:10727470). Predicted Cross Reactivity: Bovine, Rabbit Similarity: Bovine (86%), Rabbit (89%) |
Other Names | [8D6; 8D6 antigen; 8D6A; CD320; CD320 antigen; CD320_HUMAN; FDC-signaling molecule 8D6; FDC-SM-8D6; TCblR; Transcobalamin receptor] |
Gene, Accession # | [CD320], Gene ID: 51293, NCBI: NP_001159367.1, UniProt: Q9NPF0 |
Catalog # | MBS9609227 |
Price | $240, $280 |
Order / More Info | CD320 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |