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Antigenic Specificity | ACTN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha-Actinin belongs to the spectrin family of cytoskeletal proteins. It was first recognized as an actin cross-linking protein, forming an antiparallel homodimer with an actin binding head at the amino terminus of each monomer. More recently, alpha-actinin has been shown to interact with a large number of proteins involved in signaling to the cytoskeleton including those involved in cellular adhesion, migration, and immune cell targeting (1). The interaction of alpha-actinin with intercellular adhesion molecule-5 (ICAM-5) helps to promote neurite outgrowth (2). In osteoblasts, interaction of alpha-actinin with integrins stabilizes focal adhesions and may protect cells from apoptosis (3). Isoforms 1 and 4 of alpha-actinin, which are non-mu |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [ACTN1; FLJ40884; FLJ54432], [ACTN1; ACTN1; BDPLT15] |
Gene, Accession # | [ACTN1], Gene ID: 87, NCBI: P12814.2, UniProt: P12814 |
Catalog # | MBS127277 |
Price | $200, $275, $430 |
Order / More Info | ACTN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |