SOCS-4 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SOCS-4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~50 kDa of SOCS-4 protein from human and mouse origins. The other species are not tested. Cytokines induce a variety of biological responses by binding to specific cell surface receptors and activating cytoplasmic signal transduction pathways which are suppressed by other transcriptional factors. Proteins that mediate these signals from the cell surface to the nucleus include JAKs and STATs, while SOCS (Suppressor of cytokine signaling) proteins inhibit those signaling. The SOCS family comprises at least 8 members, SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). Structurally, the SOCS proteins are composed of an N terminal region of variable length and amino acid composition, a central SH2 domain |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-terminus of SOCS-4 protein from human, mouse and rat origins. |
| Other Names | [Rabbit SOCS-4; Suppressor of Cytokine Signaling 4 (SOCS4); SOCS7], [SOCS4; DKFZp686J1568; SOCS7; DKFZp686J1568] |
| Gene, Accession # | [SOCS-4], Gene ID: 122809, NCBI: NP_543143.1, UniProt: Q5H9R6 |
| Catalog # | MBS462134 |
| Price | $265 |
| Order / More Info | SOCS-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bullock, AN et al. Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Structure, 2007 Nov;15 (11):1493-504. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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