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Antigenic Specificity | SCG5 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SCG5. It was validated on Western BlotTarget Description: SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. |
Immunogen | n/a |
Other Names | [neuroendocrine protein 7B2 isoform 1; Neuroendocrine protein 7B2; neuroendocrine protein 7B2; secretogranin V; Pituitary polypeptide; Secretogranin V; Secretogranin-5; Secretory granule endocrine protein ICleaved into the following 2 chains:N-terminal peptide; C-terminal peptide] |
Gene, Accession # | [SCG5], Gene ID: 6447, NCBI: NP_001138229, UniProt: P05408 |
Catalog # | MBS3216193 |
Price | $335 |
Order / More Info | SCG5 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |