Edit |   |
Antigenic Specificity | NPHS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Podocin(NPHS2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat. Background: Podocin(PDCN) is a protein which lines the podocytes and assists in maintaining the barrier at the glomerular basement membrane. NPHS2 is a causative gene for Familial idiopathic nephrotic syndromes, which represents a heterogeneous group of kidney disorders, and include autosomal recessive steroid-resistant nephrotic syndrome, which is characterized by early childhood onset of proteinuria, rapid progression to end-stage renal disease and focal segmental glomerulosclerosis. By positional cloning, NPHS2 was mapped to 1q25-31. It is almost exclusively expressed in the podocytes of fetal and mature kidney glo |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NPHS2 (368-383aa KPVEPLNPKKKDSPML), identical to the related mouse sequence, and different from the related rat sequence by one amino acid. |
Other Names | [Podocin; nephrosis 2, idiopathic, steroid-resistant(podocin); Nephrosis 2, idiopathic, steroid resistant(podocin); nephrosis 2, idiopathic, steroid resistant; NPHS2; NPHS2 gene; PDCN; PODO_HUMAN; Podocin; SRN1], [NPHS2; NPHS2; PDCN; SRN1] |
Gene, Accession # | [NPHS2], Gene ID: 7827, NCBI: Q9NP85.1, UniProt: Q9NP85 |
Catalog # | MBS177013 |
Price | $315 |
Order / More Info | NPHS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |