Phospho-TAK1 (Ser439) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-TAK1 (Ser439) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | humanpredicted: rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Phospho-TAK1 (Ser439) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 410-444 amino acids from the human TAK1. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal tra |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase kinase kinase 7; 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1; MAP3K7; TAK1] |
| Gene, Accession # | [TAK1], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
| Catalog # | MBS9231113 |
| Price | $150 |
| Order / More Info | Phospho-TAK1 (Ser439) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sakurai H.,et al.Biochem. Biophys. Res. Commun. 243:545-549 (1998). Dempsey C.E.,et al.Biochim. Biophys. Acta 1517:46-52 (2000). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Mungall A.J.,et al.Nature 425:805-811 (2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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