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Antigenic Specificity | IRAK-M |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-IRAK-M BP [Rabbit antibody to peptide corresponding to aa 581-596 of human IRAK-M.]. This antibody recognizes human, mouse, and rat IRAK-M (68 kD). No cross-reactivity with IRAK or IRAK2. Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induce cellular responses through IL-1 receptor nad Toll-like receptors. IL-1 receptorassociated kinases (IRAK and IRAK2) mediate the activation of NF- kappa B by IL-1/Toll receptors, a key step in inflammatory and immune responses. A novel member of the IRAK family, IRAKM, is a dominant negative mutant of IRAK and inhibits IL-1 or LPS induced NF- kappa B activation. |
Immunogen | Antigen: Peptide corresponding to aa 581-596 of human IRAK-M. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194112 |
Price | $415 |
Order / More Info | IRAK-M Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |