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Antigenic Specificity | PIDD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP 665893.2). |
Other Names | [LRDD; PIDD; PIDD1] |
Gene, Accession # | [PIDD], Gene ID: 55367, NCBI: Q9HB75.2, UniProt: Q9HB75 |
Catalog # | MBS8545431 |
Price | $280 |
Order / More Info | PIDD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |