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Antigenic Specificity | Calretinin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Calretinin(CALB2) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Calretinin, also known as 29 kDa calbindin, is a vitamin D-dependent calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Calretinin is mapped to 16q22.2. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability and is a diagnostic marker for some human |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human Calretinin(234-262aa EMNIQQLTNYRKSVMSLAEAGKLYRKDLE), different from the related mouse and rat sequences by one amino acid. Ig Type: Rabbit IgG |
Other Names | [Calretinin; 29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; CALB2_HUMAN; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; Calretinin; CR; calbindin 2], [CALB2; CALB2; CR; CAL2; CAB29; CAB29; CR] |
Gene, Accession # | Gene ID: 794, NCBI: NP_001731.2, UniProt: P22676 |
Catalog # | MBS178356 |
Price | $315 |
Order / More Info | Calretinin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Parmentier M.; The human calbindins: cDNA and gene cloning.;Adv. Exp. Med. Biol. 255:233-240(1989). 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;The mouse calretinin gene promoter region: structural and functional components.;Brain Res. Mol. Brain Res. 49:175-187(1997). 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.;Biochemistry 30:656-662(1991). |