AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)
Clone[MBS-12]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nick
ImmunogenImmunogen: Recombinant full-length human Alpha fetoprotein
Other Names[Alpha fetoglobulin; FETA; HPAFP], [AFP; AFP; AFPD; FETA; HPAFP; HPAFP]
Gene, Accession #[AFP], Gene ID: 174, NCBI: NP_001125.1, UniProt: P02771
Catalog #MBS438910
Price$190, $340, $340
Order / More InfoAFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStefanova, I., Horejs-, V., Kristofov-, H., Angelisov-, P., Zizkovsky, V. and Hilgert, I. 1988. Monoclonal antibodies against human alpha-fetoprotein. Exploitation of an unusual calcium-dependent interaction with the antigen for analytical and preparative purposes. J. Immunol. Methods 111: 67-73. Lafuste, P., et al. 2002. alpha-fetoprotein gene expression in early and full-term human trophoblast. Placenta 23: 600-612
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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