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Antigenic Specificity | IL1RL1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to mouse IL1RL1. ST2 known as IL1RL1, a membrane protein, belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. Predominantly ST2 expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. |
Immunogen | n/a |
Other Names | [interleukin-1 receptor-like 1 isoform a; Interleukin-1 receptor-like 1; interleukin-1 receptor-like 1; interleukin 1 receptor-like 1; Interleukin-33 receptor alpha chain], [Il1rl1; Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ly84; St2; Ste2] |
Gene, Accession # | [IL1RL1], Gene ID: 17082, NCBI: NP_001020773.1, UniProt: P14719 |
Catalog # | MBS856836 |
Price | $280 |
Order / More Info | IL1RL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.Bergers G., Reikersdorfer A., Braselmann S., Graninger P., Busslinger M.EMBO J. 13:1176-1188(1994). 2. The IL-33/ST2 pathway: therapeutic target and novel biomarker.Kakkar R, Lee RT.Nat ?Rev Drug Discov. 2008 Oct; 7(10):827-40. Review. |