IL1RL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL1RL1
Clonepolyclonal
Host Speciesn/a
Reactive Speciesmouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to mouse IL1RL1. ST2 known as IL1RL1, a membrane protein, belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. Predominantly ST2 expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
Immunogenn/a
Other Names[interleukin-1 receptor-like 1 isoform a; Interleukin-1 receptor-like 1; interleukin-1 receptor-like 1; interleukin 1 receptor-like 1; Interleukin-33 receptor alpha chain], [Il1rl1; Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ly84; St2; Ste2]
Gene, Accession #[IL1RL1], Gene ID: 17082, NCBI: NP_001020773.1, UniProt: P14719
Catalog #MBS856836
Price$280
Order / More InfoIL1RL1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.Bergers G., Reikersdorfer A., Braselmann S., Graninger P., Busslinger M.EMBO J. 13:1176-1188(1994). 2. The IL-33/ST2 pathway: therapeutic target and novel biomarker.Kakkar R, Lee RT.Nat ?Rev Drug Discov. 2008 Oct; 7(10):827-40. Review.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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