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Antigenic Specificity | CD2AP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. |
Immunogen | Immunogen: Recombinant Human CD2-associated protein (333-426AA) |
Other Names | [CD2-associated protein; Adapter protein CMS; Cas ligand with multiple SH3 domains; CD2AP] |
Gene, Accession # | [CD2AP], Gene ID: 23607, NCBI: NP_036252.1, UniProt: Q9Y5K6 |
Catalog # | MBS7108812 |
Price | $160, $235 |
Order / More Info | CD2AP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |