PKM1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKM1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total PKM1 protein. Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa. 399~403(V-R-A-S-S) derived from Human PKM1.
Other Names[PKM; PK3; OIP3; PK2]
Gene, Accession #[PKM1], Gene ID: 5315, NCBI: NP_001193725.1, UniProt: P14618
Catalog #MBS9404561
Price$200, $255
Order / More InfoPKM1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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