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Antigenic Specificity | Human Apolipoprotein-H (beta2GPI) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | IgG fraction |
Size | 5 mg |
Concentration | IgG concentration is mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 13.4. |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is specific for beta2GPI as demonstrated by immunoelectrophoresis and ELISA. Apolipoprotein-H, also known as beta2-Glycoprotein I (beta2GPI), is a plasma glycoprotein that circulates at a concentration of 200 ug/ml (4 uM). Synthesized in the liver, beta2GPI is a single chain molecule of 48 kDa, consisting of five repeating internally disulphide-bonded structures referred to as sushi domains. Relative to other glycoproteins, beta2GPI has an unusually high content of cysteine (6.2%), proline (8.3%) and carbohydrate (19%). Almost half the circulating beta2GPI in plasma is associated with lipoproteins of all major fractions. beta2GPI has been demonstrated to bind negatively charged phospholipids, heparin and platelets. Although th |
Immunogen | Immunogen: Human beta2GPI purified from plasma. |
Other Names | [beta2-Glycoprotein-1 (APO-H), human], [APOH; APOH; BG; B2G1; B2GP1; B2G1] |
Gene, Accession # | Gene ID: 350, NCBI: NP_000033.2, UniProt: P02749 |
Catalog # | MBS512023 |
Price | $310 |
Order / More Info | Human Apolipoprotein-H (beta2GPI) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lee, NS, Brewer HB Jr., Osborne JC Jr.; beta2Glycoprotein I: Molecular Properties of an Unusual Apolipoprotein, Apolipoprotein H; JBC 258, pp 4765-4770, 1983.2. Schousboe I; beta2Glycoprotein I: A Plasma Inhibitor of the Contact Activation of the Intrinsic Blood Coagulation Pathway. Blood 66, pp 1 086-1091, 1985.3. Nimpf J, Bevers EM, Bomans PHH, Till U, Wurm H, Kostner GM, Zwaal RFA; Prothrombinase activity of human platelets is inhibited by beta2Glycoprotein I; Biochimica et Biophysica Acta 884, pp 142-149, 1986. |