Human IL-13 receptor alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IL-13 receptor alpha
Clone[10A51]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionTwo members of the type 5 subfamily of type I cytokine receptors can serve as receptors for IL-13. IL-13 can bind to IL-13 R alpha 1 (CD213a1; previously designated IL-13 R alpha or NR4) with low affinity, then recruits the IL-4 R alpha chain to form a high affinity receptor, causing downstream STAT6 activation. Alternately, IL-13 can bind IL-13 R alpha 2 (CD213a2) with high affinity; this interaction does not cause activation of STAT6, but does induce TGF-beta production. IL-13 R alpha 1 and IL-13 R alpha 2 each have three extracellular fibronectin type III domains, two cytokine receptor homology modules and a WSXWS motif typical of the class I cytokine receptor family, but IL-13 R alpha 2 has a much shorter cytoplasmic tail. IL-13 R subun
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-13R a1 extracellular domain.
Other Names[IL13RA1; NR4; CD213A1; IL-13Ra], [IL13RA1; IL13RA1; NR4; CD213A1; IL-13Ra; IL13R; IL13RA; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19]
Gene, Accession #[IL-13 receptor alpha], Gene ID: 3597, NCBI: NP_001551.1, UniProt: P78552
Catalog #MBS690805
Price$490
Order / More InfoHuman IL-13 receptor alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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