GRK 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRK 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: GRK 2 Polyclonal Antibody detects endogenous levels of GRK 2 protein. Beta-adrenergic receptor kinase 1 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Beta-adrenergic receptor kinase 1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
ImmunogenImmunogen: Synthesized peptide derived from the C-terminal region of human GRK 2 at AA range: 570-650
Other Names[Rabbit GRK 2; ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2]
Gene, Accession #[GRK2], Gene ID: 156, NCBI: NP_001610.2, UniProt: P25098
Catalog #MBS9702181
Price$130, $220, $325
Order / More InfoGRK 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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