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Antigenic Specificity | PDZK1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity (By similarity). Required for normal cell-surface expression of SCARB1. Plays a role in maintaining norm |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse PDZK1 |
Other Names | [Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; PDZ domain containing 1; CFTR-associated protein of 70 kDa; Na(+)/H(+) exchanger regulatory factor 3; Na/Pi cotransporter C-terminal-associated protein 1; NaPi-Cap1; PDZ domain-containing protein 1; Sodium-hydrogen exchanger regulatory factor 3] |
Gene, Accession # | [PDZK1], Gene ID: 59020, NCBI: NP_001139473.1, UniProt: Q9JIL4 |
Catalog # | MBS3223691 |
Price | $335 |
Order / More Info | PDZK1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |