Edit |   |
---|---|
Antigenic Specificity | Human alpha-synuclein |
Clone | [8F12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes the recombinant alpha-synuclein. Description: Mouse monoclonal antibody to human alpha-synuclein background: alpha-synuclein is a protein of unknown function. It is mainly found in neural tissue. There is a lipid-binding motif similar to that of Apolipoproteins on its N-terminal. A hydrophobic region that is the non-beta component found in amyloid aggregation in Alzheimer's disease is located at the central region of the protein. The abnormal aggregation of alpha-synuclein on brain tissue is called Lewy bodies, which are found in Parkinson's disease, dementia and multiply system atrophy. Mutated alpha-synuclein gene is found to be associated with rare familial form of Parkinson's disease. |
Immunogen | Immunogen: Recombinant human alpha-synuclein (1-140 aa) expressed in E. coli. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. |
Other Names | [Alpha-Synuclein; Mouse to human alpha-synuclein], [SNCA; SNCA; PD1; NACP; PARK1; PARK4] |
Gene, Accession # | Gene ID: 6622, NCBI: P37840.1 |
Catalog # | MBS592344 |
Price | $445 |
Order / More Info | Human alpha-synuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |