CD46 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CD46 antibody, protein, ELISA kits.
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| Antigenic Specificity | CD46 |
| Clone | [AT2G9] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, k |
| Format | Protein A purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types. |
| Immunogen | Immunogen: Recombinant human CD46 (35-313aa) purified from E. coli |
| Other Names | [Membrane cofactor protein isoform 14; AHuS2; MCP; MIC10; TLX; TRA2.10], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
| Gene, Accession # | [CD46], Gene ID: 4179, NCBI: NP_758860, UniProt: P15529 |
| Catalog # | MBS200297 |
| Price | $240, $315 |
| Order / More Info | CD46 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liszewski M.K., et al. (1991) Annu Rev Immunol 9: 431-455; Riley-Varqas R.C., et al. (2004) Trends Immunol 25 (9): 496-503; Studebaker A.W., et al. (2010) Neuro Oncol 12: 1034-1042 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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