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Antigenic Specificity | Active Caspase-3 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. |
Immunogen | Immunogen: Recombinant Protein Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4 Observed MW: 17kDa |
Other Names | [CASP3,Caspase 3,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,CPP-32,CPP32,CPP32B,Cysteine protease CPP32] |
Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
Catalog # | MBS2548892 |
Price | $110, $150, $225 |
Order / More Info | Active Caspase-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |