Active Caspase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityActive Caspase-3
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein A purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
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DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
ImmunogenImmunogen: Recombinant Protein Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4 Observed MW: 17kDa
Other Names[CASP3,Caspase 3,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,CPP-32,CPP32,CPP32B,Cysteine protease CPP32]
Gene, Accession #Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574
Catalog #MBS2548892
Price$110, $150, $225
Order / More InfoActive Caspase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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