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Antigenic Specificity | MYC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its import |
Immunogen | Immunogen: A synthetic peptide of human MYC. |
Other Names | [myc proto-oncogene protein isoform 1; Myc proto-oncogene protein; myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: NP_002458.2, UniProt: P01106 |
Catalog # | MBS8571954 |
Price | $280 |
Order / More Info | MYC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |