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Antigenic Specificity | MLF1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MLF1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLF1 |
Other Names | [myeloid leukemia factor 1 isoform 1; Myeloid leukemia factor 1; myeloid leukemia factor 1; myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1] |
Gene, Accession # | [MLF1], Gene ID: 4291, NCBI: NP_071888, UniProt: P58340 |
Catalog # | MBS3211494 |
Price | $335 |
Order / More Info | MLF1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |