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Antigenic Specificity | FOXP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. |
Immunogen | Immunogen: Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3. Buffer: FOXP3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; JM2; Forkhead box protein P3; Scurfin; forkhead box P3], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX] |
Gene, Accession # | [FOXP3], Gene ID: 50943, NCBI: NP_054728, UniProt: Q9BZS1 |
Catalog # | MBS153578 |
Price | $375 |
Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |