Mouse CD117/c-kit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD117/c-kit |
| Clone | [2B8] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD117/c-Kit. The CD117/c-kit antigen is the cell-surface receptor for Stem Cell Factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult.1-3 Signaling through SCF/c-kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells.2 A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B-cell differentiation of uncommitted hematopoietic progenitor cells.2 SCF/c-kit also participates in erythropoiesis in both the bone marrow and spleen.1 Loss-of-function mutat |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673626 |
| Price | $260 |
| Order / More Info | Mouse CD117/c-kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Broudy, V.C., et al, 1996. Blood 88:75.2. Veiby, O.P., S. D. Lyman and S. E. Jacobsen. 1996. Blood 87:3117.3. Sudo, T., et al. 1995. Oncogene 11:2469.4. Yoshida, H., et al. 1996. Development 122: 1207. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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