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Antigenic Specificity | APG5L/ATG5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Autophagy protein 5(ATG5) detection. Tested with WB in Human, Mouse, Rat. Background: Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human APG5L (82-97aa DRFDQFWAINRKLMEY), identical to the related mouse sequence, and different from the related rat sequence by one amino acid. |
Other Names | [Autophagy protein 5; autophagy related 5; APG 5; APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; APG5L; Apoptosis specific protein; Apoptosis-specific protein; ASP; ATG 5; Atg5; ATG5 autophagy related 5 homolog; Autophagy protein 5; hAPG5; Homolog of S Cerevisiae autophagy 5; OTTHUMP00000040507], [ATG5; ATG5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; APG5L; ASP] |
Gene, Accession # | [ATG5], Gene ID: 9474, NCBI: Q9H1Y0.2, UniProt: Q9H1Y0 |
Catalog # | MBS176873 |
Price | $280 |
Order / More Info | APG5L/ATG5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |