GAPDH [12D3D5] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGAPDH [12D3D5]
Clone[12D3D5]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, rabbit
IsotypeIgG
Formatbiotin conjugate
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: Biotin-GAPDH antibody is human, mouse, rat, and rabbit reactive. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. It also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH also plays a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2). GAPDH is constitutively expressed at high levels in almost all tissues a
ImmunogenImmunogen: Biotin-GAPDH antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GAPDH. Buffer: Biotin-GAPDH antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Glyceraldehyde-3-phosphate dehydrogenase; G3PDH; GAPD], [GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH]
Gene, Accession #[GAPDH], Gene ID: 2597, NCBI: NP_002037, UniProt: P04406
Catalog #MBS154515
Price$375
Order / More InfoGAPDH [12D3D5] Antibody from MYBIOSOURCE INC.
Product Specific References1. Sirover MA. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J. Cell. Biochem. 2005; 95:45-52. 2. Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu. Rev. Pharmacol. Toxicol. 2005; 45:269-90.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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