NANOG Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNANOG
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionTranscription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading
ImmunogenImmunogen: Recombinant human Homeobox protein NANOG protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30331 / sc-30332 / sc-33759
Other Names[Homeobox protein NANOG; NANOG; Homeobox transcription factor Nanog; hNanog], [NANOG; NANOG; hNanog]
Gene, Accession #[NANOG], Gene ID: 79923, NCBI: NP_001284627.1, UniProt: Q9H9S0
Catalog #MBS1493184
Price$160, $235
Order / More InfoNANOG Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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