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Antigenic Specificity | NANOG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading |
Immunogen | Immunogen: Recombinant human Homeobox protein NANOG protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30331 / sc-30332 / sc-33759 |
Other Names | [Homeobox protein NANOG; NANOG; Homeobox transcription factor Nanog; hNanog], [NANOG; NANOG; hNanog] |
Gene, Accession # | [NANOG], Gene ID: 79923, NCBI: NP_001284627.1, UniProt: Q9H9S0 |
Catalog # | MBS1493184 |
Price | $160, $235 |
Order / More Info | NANOG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |