CASP6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CASP6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Western blot analysis of extracts of Jurkat cell lines, using CASP6 antibody. Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes (1, 2). Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated (3). The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis (4,5). One of the major targets for caspase-6 is the membrane associated protein lamin A (6). The cleavage of this protein causes cell membrane malfunction, membrane blebbing and eventual cell death. |
| Immunogen | Immunogen: Recombinant protein of human CASP6 |
| Other Names | [caspase-6 isoform alpha; Caspase-6; caspase-6; caspase 6; Apoptotic protease Mch-2], [CASP6; CASP6; MCH2; MCH2; CASP-6] |
| Gene, Accession # | [CASP6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
| Catalog # | MBS419818 |
| Price | $385 |
| Order / More Info | CASP6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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