CASP4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCASP4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is " caspase 4, apoptosis-related cysteine peptidase" this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes
ImmunogenImmunogen: Recombinant protein of mouse CASP4 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[CASP-11; CASP-4; Casp11; Caspl; ich-3]
Gene, Accession #[CASP4], Gene ID: 837, NCBI: NP_001216.1, UniProt: P49662
Catalog #MBS8535959
Price$300
Order / More InfoCASP4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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