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Antigenic Specificity | CASP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is " caspase 4, apoptosis-related cysteine peptidase" this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes |
Immunogen | Immunogen: Recombinant protein of mouse CASP4 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CASP-11; CASP-4; Casp11; Caspl; ich-3] |
Gene, Accession # | [CASP4], Gene ID: 837, NCBI: NP_001216.1, UniProt: P49662 |
Catalog # | MBS8535959 |
Price | $300 |
Order / More Info | CASP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |