CD27 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD27
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionCD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.
ImmunogenImmunogen: CD27 fusion protein Ag24537
Other Names[CD27; CD27 antigen; CD27 molecule; CD27L receptor; S152; T cell activation antigen CD27; T14; TNFRSF7; Tp55]
Gene, Accession #[CD27], Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842
Catalog #MBS2540252
Price$220, $290, $435
Order / More InfoCD27 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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