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Antigenic Specificity | MRGPRX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 |
Immunogen | Immunogen: Recombinant human Mas-related G-protein coupled receptor member X2 protein |
Other Names | [Mas-related G-protein coupled receptor member X2; MRGPRX2; MRGX2] |
Gene, Accession # | [MRGPRX2], Gene ID: 117194, NCBI: NP_001290544.1, UniProt: Q96LB1 |
Catalog # | MBS7001658 |
Price | $160, $235 |
Order / More Info | MRGPRX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |