ATG14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATG14
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionRequired for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed: 18843052, PubMed: 19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed: 19270696, PubMed: 20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed: 20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed: 23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed: 23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to
ImmunogenImmunogen: Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)
Other Names[Beclin 1-associated autophagy-related key regulator1; Autophagy-related protein 14-like protein; ATG14]
Gene, Accession #[ATG14], Gene ID: 22863, NCBI: NP_055739.2, UniProt: Q6ZNE5
Catalog #MBS7050457
Price$160, $235
Order / More InfoATG14 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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