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Antigenic Specificity | ATG14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed: 18843052, PubMed: 19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed: 19270696, PubMed: 20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed: 20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed: 23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed: 23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to |
Immunogen | Immunogen: Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA) |
Other Names | [Beclin 1-associated autophagy-related key regulator1; Autophagy-related protein 14-like protein; ATG14] |
Gene, Accession # | [ATG14], Gene ID: 22863, NCBI: NP_055739.2, UniProt: Q6ZNE5 |
Catalog # | MBS7050457 |
Price | $160, $235 |
Order / More Info | ATG14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |