Edit |   |
---|---|
Antigenic Specificity | DOG CD11d |
Clone | [CA11.8H2] |
Host Species | Mouse |
Reactive Species | dog |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) Formalin, Flow Cytometry (FC/FACS), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Dog CD11d antibody, clone CA11.8H2 recognizes the canine CD11d cell surface antigen, also known as integrin alpha d subunit.The alpha d integrin (CD11d) subunit is expressed as a heterodimer with beta 2 integrin (CD18). CD11d is expressed by a sub-population of macrophages, some CD8 positive T cells and by gamma/delta T cells in the splenic red pulp. Over expression of CD11d is noted in histiocytic disorders including hemophagocytic sarcoma, described as a proliferative disorder specifically of CD11+ macrophages (Moore. et al. 2006) with macrophages demonstrating marked erythrocytic phagocytosis. Previously, canine histiocytic sarcoma were described as originating entirely from interstitial dendritic cells. Cells from animals wit |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD11d] |
Catalog # | MBS224805 |
Price | $320 |
Order / More Info | DOG CD11d Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |