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Antigenic Specificity | Human FEM1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Bat, Gibbon, bovine, dog, hamster, horse, human, monkey, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Peptide (DINYQDQIPRTLEE) corresponding to amino acids 609 to 622 of human F1Aa This sequence is identical to the corresponding sequence of mouse FEM1b. Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aa and FEM1b (1,2). F1Aa/FEM1b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aa is cleaved by CED-3 and caspase (3). FEM-1/F1Aa associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aa induces apoptosis. |
Immunogen | Immunogen Description: Synthetic peptide from human FEM1B. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig (100%); Opossum (86%). |
Other Names | [FEM1B (aa609-622) IHC-plus; FEM1B; F1AA; FEM-1 (C.elegans) homolog b; FEM1-beta; FIAA; KIAA0396; F1A-ALPHA; Fem-1 homolog b (C. elegans); Protein fem-1 homolog B; Human FEM1B], [FEM1B; FEM1B; F1AA; F1A-ALPHA; FEM1-beta; F1AA; KIAA0396; FEM1b; F1A-alpha] |
Gene, Accession # | [FEM1B], Gene ID: 10116, NCBI: NP_056137.1, UniProt: Q9UK73 |
Catalog # | MBS240353 |
Price | $530 |
Order / More Info | Human FEM1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |