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Antigenic Specificity | ERBB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported |
Immunogen | Immunogen: A synthetic peptide of human Calculated Molecular Weight: 71kDa |
Other Names | [NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19] |
Gene, Accession # | [ERBB2], Gene ID: 2064, NCBI: P04626.1, UniProt: P04626 |
Catalog # | MBS126293 |
Price | $200, $275, $430 |
Order / More Info | ERBB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |