DYRK2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DYRK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protein degradation. Functions downstream of ATM and phosphorylates p53/TP53 at 'Ser-46', and thereby contributes to the induction of apoptosis in response to DNA damage. Phosphorylates NFATC1, and thereby inhibits its accumulation in the nucleus and its transcription factor activity. Phosphorylates EIF2B5 at 'Ser-544', enabling its subsequent phosphorylation and inhibition by GSK3B. Likewise, phosphorylation of NFATC1, CRMP2/DPYSL2 and CRMP4/DPYSL3 promotes their subsequent phosphorylation by GSK3B. May p |
| Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 429-528 of human DYRK2 (NP 003574.1). |
| Other Names | [dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform 2; Dual specificity tyrosine-phosphorylation-regulated kinase 2; dual specificity tyrosine-phosphorylation-regulated kinase 2; dual specificity tyrosine phosphorylation regulated kinase 2] |
| Gene, Accession # | [DYRK2], Gene ID: 8445, NCBI: NP_006473, UniProt: Q92630 |
| Catalog # | MBS8546511 |
| Price | $280 |
| Order / More Info | DYRK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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