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Antigenic Specificity | Actinin-alpha1/2/3/4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Actinin-alpha1/2/3/4 Polyclonal Antibody detects endogenous levels of Actinin-alpha1/2/3/4 protein. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 encodes a nonmuscle, cytoskeletal, a |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Actinin-alpha1/2/3/4 at AA range: 40-120 |
Other Names | [Rabbit Actinin-alpha1/2/3/4; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1; ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; ACTN3; Alpha-actinin-3; A] |
Gene, Accession # | [ACTN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814 |
Catalog # | MBS9700650 |
Price | $250, $250 |
Order / More Info | Actinin-alpha1/2/3/4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |