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Antigenic Specificity | NUP85 (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NUP85 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-195 amino acids from human NUP85. Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade. |
Immunogen | n/a |
Other Names | [Nuclear pore complex protein Nup85; 85 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1; NUP85; NUP75; PCNT1] |
Gene, Accession # | [NUP85], Gene ID: 79902, NCBI: NP_001290205.1, UniProt: Q9BW27 |
Catalog # | MBS9217203 |
Price | $165, $370 |
Order / More Info | NUP85 (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Cronshaw J.M.,et al.J. Cell Biol. 158:915-927 (2002). Terashima Y.,et al.Nat. Immunol. 6:827-835 (2005). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Bechtel S.,et al.BMC Genomics 8:399-399 (2007). Zody M.C.,et al.Nature 440:1045-1049 (2006). |