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Antigenic Specificity | SIRP, alpha1, aa487-503 (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunocytochemistry(IHC), ELISA. Other applications not tested |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human SIRP alpha 1, 2 and 3. Species Crossreactivity: mouse and rat. Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1), SHPS-1 (2,3), MyD-1 (4), BIT (5,6) and p84 (7). SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and s |
Immunogen | Immunogen: Synthetic peptide (KPEPSFSEYASVQVPRK) corresponding to aa487-503 of human SIRPa1. Grade: Affinity Purified. Species sequence homology: bovine based on 88% homology with the immunogen sequence |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS610730 |
Price | $545 |
Order / More Info | SIRP, alpha1, aa487-503 (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |