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Antigenic Specificity | Mouse DIABLO / SMAC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse. predicted reactivity: rat (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide (SDEGADQEEEAYLRED) corresponding to amino acids 222 to 237 of murine Smac/DIABLO. Second mitochondria-derived activator of caspase (SMAC) has been implicated in the activation of apoptosis in response to cell stress. SMAC promotes CASP9 activation by binding to IAPs and removing their inhibitory activity. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. |
Immunogen | Immunogen Description: A peptide corresponding to amino acids 222 to 237 of murine Smac/DIABLO. Percent identity by BLAST analysis: Mouse (100%); Rat (94%). |
Other Names | [DIABLO / SMAC (aa222-237) IHC-plus; DIABLO; DFNA64; DIABLO-S; Diablo homolog; mitochondrial; SMAC3; Mitochondrial Smac protein; SMAC; Mouse DIABLO; SMAC], [SMAC] |
Gene, Accession # | [DIABLO], Gene ID: 56616, NCBI: NP_063940.1, UniProt: Q9NR28 |
Catalog # | MBS241266 |
Price | $530 |
Order / More Info | Mouse DIABLO / SMAC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |