SHP-1 (Ab-564) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySHP-1 (Ab-564)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total SHP-1 protein. Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human SHP-1.
Other Names[HCP; HCPH; hematopoietic cell phosphatase; Hematopoietic cell protein-tyrosine phosphatase; HPTP1C]
Gene, Accession #[SHP-1], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582
Catalog #MBS9406378
Price$200, $255
Order / More InfoSHP-1 (Ab-564) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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