RBM5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRBM5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: RBM5 antibody detects endogenous levels of total RBM5. Function: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.Subunit Structure: Co
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (82%)
Other Names[FLJ39876; G15; H37; LUCA 15; LUCA15; Protein G15; Putative tumor suppressor LUCA15; RBM 5; Rbm5; RBM5_HUMAN; Renal carcinoma antigen NY REN 9; Renal carcinoma antigen NY-REN-9; RMB 5; RMB5; RNA binding motif protein 5; RNA binding protein 5; RNA-binding motif protein 5; RNA-binding protein 5; Tumor suppressor LUCA15]
Gene, Accession #[RBM5], Gene ID: 10181, NCBI: NP_005769.1, UniProt: P52756
Catalog #MBS9604668
Price$240, $280
Order / More InfoRBM5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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