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Antigenic Specificity | NFkappaB-p100/p52 (Ab-872) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NFkB-p100 protein. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NFkB-p100. |
Other Names | [NFkB-p100/p52 (Ab-872); DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2] |
Gene, Accession # | [NFkappaB-p100/p52], Gene ID: 4791, NCBI: NP_001070962.1, UniProt: Q00653 |
Catalog # | MBS9401153 |
Price | $200, $255 |
Order / More Info | NFkappaB-p100/p52 (Ab-872) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |