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Antigenic Specificity | USP34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: USP34 antibody detects endogenous levels of total USP34. Function: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.Subunit Structure: Interacts with AXIN1 and AXIN2.Similarity: Belon |
Immunogen | Immunogen: A synthesized peptide derived from human USP34 Tissue Specificity: Expressed in brain at low level. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (94%), Xenopus (81%) |
Other Names | [Deubiquitinating enzyme 34; FLJ43910; KIAA0570; KIAA0729; MGC104459; Ubiquitin carboxyl terminal hydrolase 34; Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin specific processing protease 34; Ubiquitin specific protease 34; Ubiquitin thioesterase 34; Ubiquitin thiolesterase 34; Ubiquitin-specific-processing protease 34; UBP34_HUMAN; USP 34; Usp34] |
Gene, Accession # | [USP34], Gene ID: 9736, NCBI: NP_055524.3, UniProt: Q70CQ2 |
Catalog # | MBS9610304 |
Price | $240, $280 |
Order / More Info | USP34 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |