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Antigenic Specificity | Human Interleukin-1 receptor antagonist |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.This protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene |
Immunogen | Immunogen: Recombinant human Interleukin-1 receptor antagonist protein |
Other Names | [Interleukin-1 receptor antagonist protein; ICIL-1RA; IL1 inhibitor; INN=Anakinra IL1RN; IL1F3; IL1RA] |
Gene, Accession # | [IL1RN], Gene ID: 3557, NCBI: NP_000568.1, UniProt: P18510 |
Catalog # | MBS7005376 |
Price | $160, $235 |
Order / More Info | Human Interleukin-1 receptor antagonist Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |